Hormone Therapy for Lung Cancer Rockaway Park NY

Taking a combination form of hormone replacement therapy, which includes both estrogen and progestin, increases a woman's risk for dying from lung cancer, a new study has found. The finding stems from an analysis of data from the Women's Health Initiative trial on 16,608 postmenopausal women, aged 50 to 79, in the United States who had been randomly assigned to take either a once-daily tablet of 0.625 milligrams conjugated equine estrogen plus 2.5 mg medroxyprogesterone acetate or a placebo.

Local Companies

Winthrop-University Hospital
516-663-0333
259 First Street
Mineola, NY
Hoboken University Medical Ctr
201-418-1000
308 Willow Avenue
Hoboken, NJ
Cornerstone Of Med Arts Hosp
212-755-0200
57 West 57th Street
New York, NY
Lutheran Medical Center
718-630-7000
150 55th Street
Brooklyn, NY
Richmond University Med Ctr
718-818-1234
355 Bard Avenue
Staten Island, NY
Jacobi Medical Center
718-918-5000
1400 Pelham Parkway
Bronx, NY
St Luke'S-Roosevelt Hosp Ctr
212-523-4000
1000 Tenth Avenue
New York, NY
Cabrini Medical Center
212-995-6000
227 East 19th Street
New York, NY
South Beach Psychiatric Center
718-667-2300
777 SEaview Avenue
Staten Island, NY
New York Community Hospital
718-692-5300
2525 Kings Highway
Brooklyn, NY
Data Provided by:
  

Provided By:

SATURDAY, Sept. 19 (HealthDay News) -- Taking a combination form of hormone replacement therapy, which includes both estrogen and progestin, increases a woman's risk for dying from lung cancer, a new study has found.

The finding stems from an analysis of data from the Women's Health Initiative trial on 16,608 postmenopausal women, aged 50 to 79, in the United States who had been randomly assigned to take either a once-daily tablet of 0.625 milligrams conjugated equine estrogen plus 2.5 mg medroxyprogesterone acetate or a placebo.

After eight years, 73 women taking the hormone therapy and 40 women in the placebo group had died of lung cancer. That meant, according to the researchers, that women who took the drug were 71 percent more likely to die from the disease.

The study also found that women taking the hormone therapy were 28 percent more likely to be diagnosed with lung cancer, although the study noted that the finding was not statistically significant.

"Treatment with estrogen plus progestin in postmenopausal women ... increased the number of deaths from lung cancer, in particular deaths from non-small-cell lung cancer," concluded Rowan Chlebowski, of the Los Angeles Biomedical Research Institute at Harbour-UCLA Medical Center, and his colleagues.

The researchers urged that the findings "be incorporated into risk-benefit discussions with women considering combined hormone therapy, especially those with a high risk of lung cancer ... such as current smokers or long-term past smokers."

Dr. Apar Kishor Ganti, from the University of Nebraska Medical Center in Omaha, wrote in an accompanying editorial that "because the optimum safe duration of hormone-replacement therapy in terms of lung cancer survival is unclear, such therapy should probably be avoided in women at a high risk of developing lung cancer, especially those with a history of smoking."

In fact, Ganti questioned whether hormone therapy should be used at all.

"These results, along with the findings showing no protection against coronary heart disease, seriously question whether hormone-replacement therapy has any role in medicine today," he wrote. "It is difficult to presume that the benefits of routine use of such therapy for menopausal symptoms outweigh the increased risks of mortality, especially in the absence of improvement in the quality of life."

The study, which appears online and in an upcoming print issue of The Lancet, was released Sept. 19 to coincide with the European Cancer Organization meeting.

More information

The U.S. National Institute on Aging has more on hormones and menopause.

SOURCE: The Lancet, news release, Sept. 19, 2009

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Read Article at HealthDay.com

Related Articles
- Hormone Therapy Rockaway Park NY
Hormone replacement therapy once seemed like a wonderful means to help women age gracefully. By dosing menopausal women with estrogen and progesterone as their bodies began to produce decreased amounts of those hormones, doctors believed they could help fend off heart disease, osteoporosis and cancer.
- Drug Combo Proves Powerful Against Lung Cancer Rockaway Park NY
- Menopausal Hormone Therapy Rockaway Park NY
- Breast Cancer Treatment Rockaway Park NY
- Delayed Prostate Cancer Therapy Rockaway Park NY
- Head and Neck Cancer Treatment Rockaway Park NY
- Hormone Therapy for Prostate Cancer Rockaway Park NY
- Hormone Therapy for Breast Cancer Rockaway Park NY
- Hormone Therapy for Early Prostate Cancer Rockaway Park NY