Heart Damage Treatments Port Jefferson Station NY

During a heart attack, vessels that supply blood to the heart become blocked, preventing enough oxygen from getting through. The heart muscle dies or is permanently damaged.

Local Companies

Giridhar Korlipara
(631) 689-1400
3400 Nesconset Hwy # 105
East Setauket, NY
Kenneth Walsh
(631) 351-3782
325 Park Ave
Huntington, NY
Abhay Malhotra
(631) 979-8880
496 Smithtown Byp # 101
Smithtown, NY
William Cicio
(631) 444-9600
3001 Expressway Dr N
Hauppauge, NY
Suresh Krishnamurt
(631) 444-0580
26 Research Way
East Setauket, NY
Ronald Cohn
(631) 368-2818
10 Andrea Ln
Greenlawn, NY
Hachiro Nakamura
(631) 351-3777
325 Park Ave
Huntington, NY
Scott Gottesfeld
(631) 385-0022
172 East Main St
Huntington, NY
Jyoti Ganguly
(631) 979-8880
496 Smithtown Byp # 101
Smithtown, NY
Kiran Pandey
(631) 689-8333
Suny At Stony Brook Univ Hosp
Stony Brook, NY
Data Provided by:
  

Provided By:

Doctors have been unable to help injured heart tissue renew itself after a heart attack -- until now.

During a heart attack, vessels that supply blood to the heart become blocked, preventing enough oxygen from getting through. The heart muscle dies or is permanently damaged.

But researchers at Children's Hospital Boston report progress toward someday being ale to regenerate heart tissue after a heart attack or heart failure and even in children who are born with congenital heart defects.

In a study on mice, they showed that neuregulin 1 (NRG1), a growth factor involved in the development of the heart and nervous system, can fuel heart-muscle growth and recovery of cardiac function when injected after a heart attack.

This is a significant development because coronary heart disease, which causes heart attack and angina, is the leading cause of death in America.

After birth, heart-muscle cells stop dividing and proliferating. But experts, led by Dr. Bernhard Kuhn and Kevin Bersell of the cardiology department at Children's, restarted the cell cycle with NRG1, spurring the heart-muscle cells to divide and make copies of themselves.

When the team injected NRG1 into live mice once a day for three months after the animals had heart attacks, heart regeneration increased and the pumping function improved, compared with untreated mice.

In addition, the NRG1-injected mice did not show some common aftereffects of heart failure.

The study, funded by the cardiology department at Children's Hospital Boston, the Charles Hood Foundation and the American Heart Association, found that cell growth does not have to come from stem cells. A report on the research appears in the July 24 issue of Cell.

"Although many efforts have focused on stem cell-based strategies, our work suggests that stem cells aren't required and that stimulating differentiated cardiomyocytes [heart-muscle cells] to proliferate may be a viable alternative," Kuhn, the study's senior investigator, said in a news release from the hospital.

More information

The American Heart Association has tips on maintaining a healthy heart.

SOURCE: Children's Hospital Boston, news release, July 23, 2009

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Read Article at HealthDay.com

Related Articles
- Heart Disease Port Jefferson Station NY
Heart disease is the leading cause of death in the United States, killing one person every 34 seconds. The term heart disease encompasses more than just one condition. It encompasses eight different conditions affecting the heart, all of which can be fatal.
- Heart Surgery Risks Port Jefferson Station NY
- Solution For Psoriasis Port Jefferson Station NY
- Heart CT Scan Port Jefferson Station NY
- Heart Scans Port Jefferson Station NY
- Heart Attack Symptoms Port Jefferson Station NY
- EBT Heart Scan Port Jefferson Station NY
- Damaged Heart Muscles Port Jefferson Station NY
- Age Spot Removal Port Jefferson Station NY