Heart Damage Treatments Canandaigua NY

During a heart attack, vessels that supply blood to the heart become blocked, preventing enough oxygen from getting through. The heart muscle dies or is permanently damaged.

Local Companies

Mark Goldberger
(212) 932-4542
5141 Broadway
Newark, NY
(315) 789-5758
1150 State Route 5 And 20
Geneva, NY
Roger Kneale Vince, MD
360 Parrish St Ste 307
Canandaigua, NY
David Edmond Conrey, MD
200 North St # 101
Geneva, NY
Frederick Thomas Zugibe, MD
201 Frey St
Newark, NY
Darlene Go
(718) 270-1568
277 Watchung Ave.
Bloomfield, NY
(315) 462-3571
4 Coulter Road
Clifton Springs, NY
(585) 218-0128
17 Cobblefield Way
Pittsford, NY
Mark Stanley Rosenzweig, MD
4 Coulter Rd
Clifton Springs, NY
Mary Jose Pudusseri, MD
4 Coulter Rd
Clifton Springs, NY
Data Provided by:

Provided By:

Doctors have been unable to help injured heart tissue renew itself after a heart attack -- until now.

During a heart attack, vessels that supply blood to the heart become blocked, preventing enough oxygen from getting through. The heart muscle dies or is permanently damaged.

But researchers at Children's Hospital Boston report progress toward someday being ale to regenerate heart tissue after a heart attack or heart failure and even in children who are born with congenital heart defects.

In a study on mice, they showed that neuregulin 1 (NRG1), a growth factor involved in the development of the heart and nervous system, can fuel heart-muscle growth and recovery of cardiac function when injected after a heart attack.

This is a significant development because coronary heart disease, which causes heart attack and angina, is the leading cause of death in America.

After birth, heart-muscle cells stop dividing and proliferating. But experts, led by Dr. Bernhard Kuhn and Kevin Bersell of the cardiology department at Children's, restarted the cell cycle with NRG1, spurring the heart-muscle cells to divide and make copies of themselves.

When the team injected NRG1 into live mice once a day for three months after the animals had heart attacks, heart regeneration increased and the pumping function improved, compared with untreated mice.

In addition, the NRG1-injected mice did not show some common aftereffects of heart failure.

The study, funded by the cardiology department at Children's Hospital Boston, the Charles Hood Foundation and the American Heart Association, found that cell growth does not have to come from stem cells. A report on the research appears in the July 24 issue of Cell.

"Although many efforts have focused on stem cell-based strategies, our work suggests that stem cells aren't required and that stimulating differentiated cardiomyocytes [heart-muscle cells] to proliferate may be a viable alternative," Kuhn, the study's senior investigator, said in a news release from the hospital.

More information

The American Heart Association has tips on maintaining a healthy heart.

SOURCE: Children's Hospital Boston, news release, July 23, 2009

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Read Article at HealthDay.com

Related Articles
- Solution For Psoriasis Canandaigua NY
What happens to a person who is suffering from psoriasis is that the cells of the skin are regenerating at a very rapid rate and this causes an excess build up of skin on the surface so causing the appearance scaly skin, inflammation and the itching occurs because of the excess skin which the body is just not able to handle.
- Heart Attack Symptoms Canandaigua NY
- Heart Disease Canandaigua NY
- Heart CT Scan Canandaigua NY
- Damaged Heart Muscles Canandaigua NY
- Age Spot Removal Canandaigua NY
- Heart Scans Canandaigua NY
- Heart Surgery Risks Canandaigua NY
- EBT Heart Scan Canandaigua NY