Folotyn for Non-Hodgkin's Lymphoma Buffalo NY

The drug Folotyn (pralatrexate) has been approved to treat Peripheral T-cell Lymphoma (PTCL), an often aggressive form of non-Hodgkin's lymphoma, the U.S. Food and Drug Administration said Friday. The drug, given accelerated approval because it treats an unmet medical need, was sanctioned for people whose disease has returned or hasn't responded to other types of chemotherapy, the agency said in a news release.

Local Companies

Cyrus Irani
(716) 845-2300
Elm And Carlton St
Buffalo, NY
Naoyuki Gregory Saito
(716) 689-1901
Elm And Carlton St
Buffalo, NY
Frederick Hong, MD
716-565-0355
45 Spindrift Dr Ste 100
Williamsville, NY
Martin Brecher, MD
716-845-2333
Carlton and Elm St,
Buffalo, NY
Kunle Odunsi, MD
716-845-3497
Elm and Carlton St
Buffalo, NY
Ashwani Rajput
(716) 689-1901
Elm And Carlton St
Buffalo, NY
Steven Joseph Gregoritch
(716) 565-9999
45 Spindrift Dr
Williamsville, NY
Sivakumar Y V Reddy, MD
716-688-6161
6161 Transit Rd Ste 6
East Amherst, NY
Amy Papalia Early, MD
716-630-1029
295 Essjay Rd
Buffalo, NY
Helen Koyu Chen, MD
716-898-5500
426 Grider St
Buffalo, NY
Data Provided by:
    

Provided By:

FRIDAY, Sept. 25 (HealthDay News) -- The drug Folotyn (pralatrexate) has been approved to treat Peripheral T-cell Lymphoma (PTCL), an often aggressive form of non-Hodgkin's lymphoma, the U.S. Food and Drug Administration said Friday.

The drug, given accelerated approval because it treats an unmet medical need, was sanctioned for people whose disease has returned or hasn't responded to other types of chemotherapy, the agency said in a news release.

PTCL strikes fewer than 9,500 people each year in the United States, the FDA said. The disease affects a type of white blood cell, called a T-cell, involved in the body's disease-fighting immune system.

Approval of Folotyn was based on clinical data showing it reduced tumor size in 27 percent of 109 people with PTCL who were studied. The most common adverse reactions included sores of the lips, mouth and digestive tract, low white blood cell counts, fever, nausea and fatigue.

Since the drug can harm a fetus, women taking Folotyn should avoid becoming pregnant, the FDA said. Anyone taking the drug should also take folate and vitamin B12 supplements to help reduce irritation of the mucous membranes.

Folotyn is produced by Colorado-based Allos Therapeutics, which is required to conduct additional studies of tumor shrinkage and life expectancy, the agency said.

More information

The FDA has more about this drug.

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Read Article at HealthDay.com

Related Articles
- Donor Stem-Cell Transplant for Acute Myeloid Leukemia Buffalo NY
For most patients with acute myeloid leukemia (AML) who come out of remission, donor stem cells appear to offer the best shot at survival, a new analysis shows.
- Green Tea and Hematologic Malignancies Buffalo NY