Damaged Heart Muscles Ozone Park NY

Researchers have genetically engineered cells that help form scar tissue after a heart attack into a type of cell that does just the opposite -- repairs damage to the heart muscle.

Local Companies

Robert Pass
(212) 305-9807
3959 Broadway
New York, NY
Gina Wang
(212) 682-3753
345 E 37Th St # 310
New York, NY
Frederic Dennis Regan
(718) 351-1136
347 Edison St
Staten Island, NY
F Lajam
(718) 721-1500
3141 45Th St
Long Island City, NY
Kevin Marzo
(516) 663-2396
120 Mineola blvd
Mineola, NY
Joseph Saleeb
(201) 339-4811
696 Avenue C
Bayonne, NJ
Robert Bochner Roven
(212) 371-8516
654 Madison Ave # 809 # 6
New York, NY
Omar Jaraki
(630) 527-8782
99 Memphis Avenue
Staten Island, NY
Evan Schwarzwald
(516) 482-6747
488 Great Neck Road, Suite 300
Great Neck, NY
Chukwuemeka Nwabuebo
(718) 771-6133
1166 Eastern Pkwy.
Brooklyn, NY
Data Provided by:
  

Provided By:

Researchers have genetically engineered cells that help form scar tissue after a heart attack into a type of cell that does just the opposite -- repairs damage to the heart muscle, a new study in mice shows.

The research team from the Mayo Clinic in Rochester, Minn., reprogrammed fibroblasts -- cells that play a role in scarring -- into becoming induced pluripotent stem (iPS) cells, which are stem cells that have been converted from adult cells.

The iPS cells were then transplanted into damaged mouse hearts, where they engrafted after two weeks. After four weeks, the mice hearts had improved structure and function, according to the study authors.

The iPS cells improved heart muscle performance, halted progression of structural damage to the already damaged heart and regenerated tissue at the site of damage, the researchers said.

"This study establishes the real potential for using iPS cells in cardiac treatment," study author Dr. Timothy Nelson said in a Mayo Clinic news release. "Bioengineered fibroblasts acquired the capacity to repair and regenerate infarcted hearts."

This study, which is reported online in the journal Circulation, was the first time iPS cells were used to repair heart tissue. Previous studies have investigated using iPS cells to treat Parkinson's disease, sickle cell anemia and hemophilia A.

Because iPS cells are derived from the patient, there is no risk of rejection or need for anti-rejection drugs, the researchers noted.

The hope is to one day be able to use iPS cells to repair injuries, helping to alleviate the demand for organ transplantation.

"This iPS innovation lays the groundwork for translational applications," senior study author Dr. Andre Terzic, Mayo Clinic physician-scientist, said in the same news release.

More information

The American Heart Association has more on heart attacks.

SOURCE: Mayo Clinic, news release, July 20, 2009

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Read Article at HealthDay.com

Related Articles
- Heart Attack Symptoms Ozone Park NY
Heart attacks are something that can be inherited from others in your family or you can create a world where you are eating and leading the lifestyle that is going to lead to a heart attack. Heart attack symptoms in every day life are to be introduced in the following article. Read on to learn what people can do with the disease.
- Heart Damage Treatments Ozone Park NY
- Anxiety Symptoms Ozone Park NY
- Heart Disease Ozone Park NY
- EBT Heart Scan Ozone Park NY
- The Best Way To Breathe Ozone Park NY
- Leading a Heart Healthy Lifestyle Ozone Park NY
- Heart Scans Ozone Park NY
- Heart CT Scan Ozone Park NY